Research Centre for Molecular Medicine
University of Debrecen
Life Science Building
Egyetem tér 1.
4010 Debrecen
Hungary

Phone: + 36 52 512 900 / 62733

E-mail: gulyasj@dote.hu
Course on Studying Protein-Protein Interactions by Advanced Light Microscopy and Spectroscopy
EMBO Lecture Course, Molecular and Cellular Biology from Plant to Human Cells
August 2011, Debrecen
<< 2010 September  >>
M
T
W
T
F
Sa
Su
 12345
6789101112
13141516171819
20212223242526
27282930 

PROJECT ACTIVITIES

 

JOINT LAB MEETING WITH STRATEGIC PARTNER HENRY WELLCOME LABORATORIES OF STRUCTURAL BIOLOGY, UNIVERSITY OF LEICESTER, UK

 

Cross-collaborative joint lab meeting with seminars, presentations given by lab members and discussion on further possibilities.

               

 

 

TWINNING VISIT AND PHD SYMPOSIUM OF THE DOCTORAL SCHOOL OF MEDICINE

Junior guest researchers from Twinning Partners (EMBL, DKFZ) visited the RCMM and also took part at the Symposium where they could share the details of their research, their techniques used and their research results with junior researchers of the RCMM.

Please click here to download the program and the abstracts.

Please click here to download the full program booklet.

 

 

JOINT LAB MEETING WITH STRATEGIC PARTNER UNIL, THE CENTRE FOR INTEGRATIVE GENOMICS, SWITZERLAND

 

Cross-collaborative joint lab meeting with seminars, presentations given by lab members and discussion on further possibilities.

   

   

 

VISITING RESEARCHERS AT THE RCMM

In May, 2010, Dr. Biserka Mulac-Jericevic and Dr. Zeljko Jericevic (University of Rijeka) visitied the RCMM and gave two seminars in the framework of the Tankó Béla Seminar Series. Intereseted parties filled the Library of the RCMM and the event was also a great opportunity to have a closer look at each other's research and build further collaborations.

The title of the presentations was the following:

Dr. Biserka Mulac-Jericevic: Immunomodulatory and the Transcriptional Effects of Progesterone through Progesterone Receptors in Early Pregnancy

Dr. Zeljko Jericevic: Novel Algorithms for High Throughput Data Analysis with Examples for FLIM and MRI

 

 

ADVISORY BOARD MEETING

 

The Advisory Board Meeting of the MOLMEDREX Project took place on April 29, 2010. WP leaders of the project introduced the project results and a discussion on the results and the future possibilities also took place.

 

WEEK OF INNOVATIVE REGIONS IN EUROPE - GRANADA, SPAIN - MARCH 14-16, 2010

MOLMEDREX was present at the Week of Innovative Regions, in March, 2010 with a poster presentation.

The aim of this three­day meeting (from 15 to 17 March) was to define good practices for the correct use of the structural funds applied to R&D&i in national and regional terms. Duration: 3 days 15 March: From "synergies from policies” to “synergies from actions"The political vision and the point of view of the main players. 16 March: Parallel REGPOT and REGIONS sessions with practical cases presented and round-table discussions. 17 March: Discussion on best practices and possible synergies between structural funds, the Framework Programme and the Innovation and Competitiveness Programme. Conclusions and Recommendations.


The week focused on how to move from “synergies from policies” to “synergies from actions” in order to optimise the use of existing EU instruments in the area of R&D and to succeed in making the regions the real protagonists in building the knowledge society.
 
Please click here to download the poster of MOLMEDREX project. 
 
 
 

TWINNING MEETING

3-day-long meeting with Twinning Partners: Vladimir Benes (EMBL), Jörg Langowski (DBM, DKFZ), Rainer Pepperkok (EMBL), Stefan Terjung (EMBL), Katalin Tóth (DBM, DKFZ).

Official program for December 1, 2009:

8:45 Guests’ arrival at the Medical and Health Science Center of the University of Debrecen

8:50-9:10 Opening Remarks: The Research Center for Molecular Medicine and the MOLMEDREX project 

9:10-9:30 The Debrecen Clinical Genomics Center, genomics of complex diseases and nuclear receptor regulated gene expression in immune cells (László Nagy)

9:30-9:50 Skin research at RCMM: TRP channel signaling and the Endocannabinoid system in human skin cells (Tamás Bíró)

9:50-10:10 Imaging facilities at RCMM, IL-2/IL-15 receptor assembly and signaling in T cells is affected by the molecular microenvironment (György Vámosi)

10:10-10:30 Oxidative stress signaling: role of poly(ADP-ribosyl)ation (Lászlo Virág)

10:30-11:30 Discussion

11:30 Press Conference

13:30-13:50 Introduction of the Division Biophysics of Macromolecules, DKFZ. Fluorescence correlation spectroscopy applications in cell biology: protein-protein interactions and protein mobility (Jörg Langowski, DBM, DKFZ)

13:50-14:10 Structural diversity of nucleosomes detected by single pair FRET (Katalin Toth, DBM, DKFZ)

14:10-14:30 Illuminating the secretory pathway (Rainer Pepperkok, EMBL)

14:30-14:50 Imaging and Analysis Resources in the ALMF (Stefan Terjung, EMBL)

14:50-15:10 The Genomic Core Facility of EMBL (Vladimir Benes, EMBL)

15:10- Visiting RCMM laboratories, discussion  

             

 

GENESPRING COURSE, MAY 2009

Workshop on novel methods (bioinformatics of microarray analyse) in biomedical research for different RCMM research groups. 

Type of course: local, practical

Teacher: Danielle Fletcher, Application Engineer at Agilent Biotechnologies.

                         

 

 

EQUIPMENT UPGRADE AT THE RCMM

 

Genomics Core Facilty

Microarray Platform provides  a platform for  chip-based genomic analyses. 

       

 Advanced Imaging

TIRF-PALM Microscope Purchase in progress (ongoing public procurement process)

 Features:

  • superresolution (20-50 nm), single molecule sensitivity
  • high signal-to-noise ratio for membrane protein detection
Andor iXon EM DU-897 back-illuminated EMCCD camera – already purchased  

 

 

HTS Core Facility

UV Irradiator provides controlled irradiation of keratinocytes with preset doses of UVA or UVB 

NO Analyzer measures nitric oxide (NO), nitrite, nitrate and nitrosothiols in biological fluids (media, cell lysate, serum) and in exhaled breath with high sensitivity (low nanomolar range)

Liquid dispenser (thermo) dispenses solutions (e.g buffers, media, reagents; 5-395 ul) into 96 well plates

FlyScreen Patch Clamp Platform: The new robotized patch-camp system represents an entirely new screening platform for measuring both voltage- and ligand-gated as well as temperature-activated channels. The system features a multi-channel recording surface, fully robotized and extremely rapid (<50 ms) liquid transfer system, proper temperature-control, agile internal sample handling, and elevated instrument intelligence. 

  

 

LAUNCH OF UPDATED RCMM WEBSITE AND MOLMEDREX WEBSITE

The updated RCMM website and the MOLMEDREX project website was launched in June, 2009.

 

LAUNCH OF MOLMEDREX EU FP7 PROJECT

MOLMEDREX porject was launched on May 1, 2009.